Apoptosis of Vascular Cells by Oxidized LDL
نویسندگان
چکیده
منابع مشابه
Apoptosis of vascular cells by oxidized LDL: involvement of caspases and LOX-1 and its implication in atherosclerotic plaque rupture.
Atherosclerotic plaque rupture followed by thrombus formation is a key event in the onset of acute coronary syndrome.1 Apoptotic death of smooth muscle cells in the fibrous cap of the atherosclerotic plaque, in addition to degradation of extracellular matrix proteins by matrix metalloproteinases (MMPs), appears to be involved in atherosclerotic plaque rupture.1 Oxidized LDL (Ox-LDL) has been im...
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متن کاملThe preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA.
In the present study we try to define the optimal conditions for preparation of copper-oxidized low-density lipoprotein (oxLDL) to be used for the assay of oxLDL antibodies by enzyme immunoassay (EIA). Oxidation of LDL was monitored by measuring the formation of conjugated dienes at 234 nm and the generation of fluorescent products with emission at 430 nm when excitation is performed at 360 nm....
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2004
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000119804.92239.97